Can foreign donors donate anti-epidemic materials to China without import duties?

  Some materials donated by overseas donors for poverty alleviation and charity can be exempted from import duties and import value-added tax.

  These include medical materials: basic medical drugs, basic medical devices, medical books and materials directly used to treat diseases of poor patients or endemic diseases in poverty-stricken areas, and basic medical care and public sanitation.

  ("Questions and Answers on Overseas Chinese Policies and Regulations")

  [serving overseas Chinese is all in the treasure of overseas Chinese]

30,000 gas stations enter the market to change electricity, and Sinopec wants new energy car companies to hand over half their lives?

Image source @ vision china

Text | Jinjiao Finance, Author | Xiao Di

A car saves 70,000 yuan and 30 seconds, and the subsidy is not limited by price … …

With the help of policies, enterprises and giants, the ideal mode of replacing electricity and replenishing energy for new energy vehicles is accelerating from B-end to C-end.

Recently, Sinopec, one of the "three barrels of oil", has added power generation, transmission and power supply business to its business scope, selling automobiles, motor vehicle charging and new energy vehicle power exchange facilities.

This means that,The oil sales giant will officially enter the power exchange..

On December 7, Sinopec Guangzhou Jinlong Gas Station was unveiled after the revision and upgrade. This is the 1000th charging and replacing power station and the 1000th photovoltaic power station completed and put into operation by Sinopec. This gas station is equipped with the second generation power exchange technology, which can exchange power for up to 312 Weilai cars every day, and the owner doesn’t even need to get off the bus during the power exchange process.

By 2025, Sinopec plans to build 5,000 charging and replacing power stations and 7,000 photovoltaic power stations.

The scene described by Zhang Yuzhuo, the chairman of China Petrochemical Company, seems to be somewhat idealistic: "China Petrochemical Company has more than 30,000 gas stations in the country, and will embrace the general trend of energy reform, and gradually deploy power exchange facilities in gas stations, so that users of new energy vehicles can change electricity as easily as refueling."

Back in 2011, domestic electric vehicles have just started. The State Grid has announced that charging stations should adopt the mode of replacing electricity with charging as a supplement to reduce the burden on urban power grids, and some experts have proposed it."integration of oil and electricity"The idea of rational allocation of land resources.

At that time, the new energy car track was not as crowded as it is now. The players were mainly state-owned enterprises, and the use scenarios were still limited to buses and taxis. However, the power exchange mode has been proved to be a false proposition.

In addition to the cost, the biggest problem encountered by this model is that the battery standards are not uniform, the battery manufacturers that each electric vehicle cooperates with are different, and the battery specifications produced are different.The capacity of a power exchange station is limited, so it is impossible to give consideration to both brand and quantity, and the most basic scale is difficult to achieve..

Today, these problems still exist, even with more and more players, the battery specifications that were difficult to unify in the past have become even more embarrassing.

Time has passed. When the new energy automobile industry, which encounters new obstacles in its development, meets the oil giant that needs to be turned around urgently, can the stagnant water of changing electricity create new ripples?

The answer is extremely difficult, because it is equivalent to the half-life of the car company.

It is a historical necessity that power exchange is brought up again. At present, the mainstream charging mode is far from meeting the energy demand of new energy vehicles.

An electric car becomes an "electric dad" and only needs a long trip.

During this year’s National Day holiday, the most famous news about new energy vehicles was that electric car owners fought for charging piles, and charged for one hour and stood in line for four hours … … In the face of the surge in energy demand, chronic diseases such as insufficient construction of public charging piles and lack of operation are exposed.

Over the years, charging piles have continued to catch up with new energy vehicles, but the pace is obviously not big enough.The data shows that the vehicle-pile ratio of new energy vehicles and charging piles has dropped from 7.84 in 2015 to 2.93 in 2020. Everbright Securities predicts that by 2030, the vehicle-pile ratio will gradually drop to 2, that is, two vehicles share a charging pile, but this is far from a reasonable ratio of 1.

According to the data released by China Electric Vehicle Charging Infrastructure Promotion Alliance, as of October this year, the cumulative number of charging infrastructure in China was 2.253 million, up 50.4% year-on-year. According to the data of the Ministry of Industry and Information Technology, in October this year, the production and sales of new energy vehicles were 397,000 and 383,000 respectively, an increase of 130% year-on-year.

In addition, these data also contain many widely criticized "zombie piles", that is, charging piles that are damaged but not repaired in time.

In this context, the more convenient power exchange mode has regained attention.

In 2019, the Ministry of Industry and Information Technology encouraged the pilot of the power exchange model, the policy was opened, and the market began to respond quickly.

Enterprise investigation shows that there are 67,500 existing power exchange-related enterprises in China, of which 3,710 were added in 2019, a year-on-year increase of 27.98%; In 2020, there will be an increase of 16,600, a year-on-year increase of 348.71%;In the first 10 months of this year, it increased by 33,600, a year-on-year increase of 184.83%..

The market scale is rising. According to Toubao Research Institute, in 2020, China’s new energy vehicle power exchange market will be only 38.2 billion yuan, but by 2030,The scale of power exchange market will reach 1,035.6 billion., an increase of 27 times in ten years.

Power exchange enterprises can be roughly divided into two categories: third-party operators facing B-end, such as Aodong New Energy and Hangzhou Botan Technology, and OEMs facing C-end, such as Weilai, BAIC, which has been exploring the field of power exchange for many years, and Nezha, Tucki &hellip, which are planning to change power; …

However, in the field of power exchange, no matter the size of the enterprise, it faces a dilemma — —have a deficit. Beiqi New Energy once said that,The construction cost of a power station is nearly 10 million yuan.The cost of battery reserve reached 3.22 million yuan. Huge capital investment and a long investment return period of 5-6 years pose great challenges to enterprises.

Among the enterprises listed above, Aodong is the largest power exchange operator in China. Although it has received large orders from state-owned enterprises such as BAIC and SAIC in the past five years, it is only profitable in Xiamen and Guangzhou, and the utilization rate of power exchange stations in most cities is below 60%. Bertram Technology is also looking for mergers and acquisitions.

In terms of vehicle manufacturers, since 2019, Weilai has laid out nearly 500 power stations across the country. Without considering land rent, labor costs, equipment depreciation, maintenance and other expenses, the construction cost of a single power station is about 2 million yuan. In this way,Weilai has invested at least 1 billion yuan in power exchange in the past three years..

Weilai once proposed to build 1,100 power exchange stations nationwide in 2020, but until now, half of this goal has not been achieved.

As a dawn of the power exchange industry, before this high-profile plan was written into the business scope, Sinopec’s power exchange layout has begun.

In April this year, Sinopec first signed a strategic cooperation agreement with Aodong, clarifying that the two sides will carry out all-round and in-depth cooperation around the construction and operation of power exchange stations, the upgrading of energy replenishment technology and the innovation of business models. In the future, a "national power exchange service network" will be built. In July, the first batch of power exchange stations jointly operated by Aodong and Sinopec landed in Shanghai and Chongqing. Coincidentally, Wei Lai also chose to hold the giant’s thigh after going through a difficult fight alone. Also in April, Sinopec and Weilai cooperated to build Beijing Sinopec Chaoying Station, which was officially put into operation.

At present,It is too early to say that such cooperation is a "win-win", but it is also a "take what you need".

In Sinopec, as Zhang Yuzhuo said, supporting electricity exchange is a strategy for traditional oil companies to embrace the general trend of energy reform; For players in the power exchange industry, one of the most intuitive benefits is that Sinopec’s gas stations all over the country have solved the most troublesome problem of site selection and rent for power exchange. In addition, with the support of state-owned capital, the long road of burning money for power exchange can also be easier.

Almost all areas of new energy vehicles areStart with policy and thrive on policy..

In 2019, the policy pointed out the direction for various enterprises in the power exchange industry. After that, the gradually complete top-level design installed engines and insurance for the development of power exchange.

In April 2020, the Ministry of Finance, the Ministry of Industry and Information Technology and other departments promulgated a new version of the subsidy policy for new energy passenger cars, stipulating that the price of vehicles before subsidies should be below 300,000 yuan (including 300,000 yuan).However, vehicles in the power exchange mode enjoy the green light of the policy and are not subject to price restrictions.. Subsequently, the power station was included in the category of "new infrastructure".

In November, 2020, the State Council promulgated the New Energy Automobile Industry Development Plan (2021-2035), which clearly put forward "strengthening the construction of power exchange infrastructure" and "encouraging the development of power exchange mode application". In March this year, adding charging piles and changing power stations was written into the government work report.

In addition, relevant standards have gradually landed. In April this year, the Ministry of Industry and Information Technology, the National Automobile Standardization Technical Committee and other departments issued the first basic general standard in the field of power exchange, "Safety Requirements for Power Exchange of Electric Vehicles", which was implemented on November 1.

The significance of building a power exchange station is not only to replenish energy.

From a more macro perspective,The significance of power exchange lies in centralized management of power batteries and building a system for power batteries.. This system includes production, assembly, charging, maintenance, monitoring, and the most difficult problem of power battery recycling, and finally realizes the cascade utilization of power batteries.

Ten years ago, the plan of "replacing electricity" by State Grid was based on the idea of "cutting peaks and filling valleys", that is, building charging and replacing power stations near substations to avoid a big impact on the distribution network; In the urban center where land resources are tight or the power grid is difficult to expand and transform, a centralized battery charging station will be built by relying on substations in the suburbs.

Today, relying on the construction of gas stations to change power stations is essentially throughDistributed energy storage, to reduce the burden of urban power grid.

Ecological chain of power exchange business (Source: Everbright Securities)

From the micro level, on the one hand, power exchange is a kind ofSafer way to replenish energy. According to "Analysis of Fire Accidents of Electric Vehicles in 2020", according to incomplete statistics, in 2020, the media reported 124 fire accidents of new energy vehicles, of which 23% were accidentally burned during charging.

In this mode, the charging environment of the battery can be controlled, and the battery failure can be detected in time to reduce the risk of spontaneous combustion.

On the other hand,The power exchange mode is undoubtedly a kind of high efficiency, even exceeding the traditional fuel vehicle.And it is more conducive to the way to prolong the battery life. At present, the emergency fast charging time of new energy vehicles is 1-2 hours, and the full charging time is 6-8 hours, but the high voltage DC fast charging method is a kind of damage to the battery.

Back to the most fundamental problem, the underlying logic of power exchange lies in"separation of vehicle and electricity"That is to subvert the relationship between power batteries and people — —From buying in the past to renting..

Take Weilai’s power exchange mode as an example, the owner only needs to bear the "battery rental service fee". The data shows that the price of a seven-seat version of ES8 is close to 470,000 yuan. If you rent Weilai’s battery,The optional battery pack with a battery life of 420 kilometers can be 70,000 yuan cheaper, and the optional battery pack with a battery life of 580 kilometers can be 128,000 yuan cheaper..

They can afford 71.4 months and 86.5 months’ rent respectively.

At present, the service life of the lithium battery pack carried by new energy vehicles is generally between 3 and 5 years.

For consumers, this greatly reduces the price of new energy vehicles and improves the service life of new energy vehicles.

It can be seen that the ultimate goal of power exchange policy support,Or lower the purchase threshold of new energy vehicles to solve the current energy anxiety..

Last year, the production and sales of automobiles in China were 25.225 million and 25.311 million respectively, but the production and sales of new energy vehicles were only 1.366 million and 1.367 million respectively, among which the production and sales of pure electric vehicles were 1.105 million and 1.115 million respectively, that is to say, pure electric vehicles only accounted for 4.4% of the annual sales, while new energy vehicles accounted for 5.4%, and fuel vehicles remained the mainstream of the automobile market.

Obstacles such as high price and less energy-supplementing infrastructure make the market not enthusiastic about new energy vehicles.

And as the 3060 carbon neutral target gets closer and closer,All kinds of problems from application to popularization of new energy vehicles are being solved rapidly under the dual effects of planning and market..

Almost everything is ready, but the most critical east wind — — Industry standardization has not come yet. Standardization can not be achieved, which means that the marginalized position of power exchange in the system can not be changed.

As one of the three major structures of electric vehicles, power battery has always been regarded as a moat for enterprises by OEMs.

Almost all car companies hope to increase product selling points by designing batteries with larger capacity, stronger performance and lower cost. Tesla’s battery team was set up in 2004, 12 years earlier than the self-developed chip. The news that its high-capacity 4680 battery has been developed for many years has attracted the attention of the global market. In China, although BYD’s self-developed "blade battery" has been questioned, it still contributed to the soaring share price of 300% last year. In the first half of this year, BYD Han’s sales with "blade battery" increased by more than 200% year-on-year.

In fact, battery standardization means letting automakers give up most of their power to define their own products.That’s why the power exchange was opposed by the automobile factory as early as ten years ago.

However, this time is different.

Under the goal of "double carbon", the strength of national policies and state-owned capital is overweight, which is standardizing manufacturing conditions and clearing obstacles for power exchange. In July last year, at the press conference in the State Council, the Ministry of Industry and Information Technology said that it would continue to vigorously promote the infrastructure construction of charging and replacing electricity, encourage enterprises to develop models of replacing electricity according to applicable scenarios, and support pilot projects in places like Beijing and Hainan for promotion. After that, the governments of Anhui, Yunnan, Shanghai, Hainan and Henan successively put forward the construction plan of power exchange station.

The determined trend is making enterprises in the field of power exchange bolder than in the past.— — In addition to in-depth cooperation with Sinopec, Weilai announced that it will deploy more than 4,000 power stations worldwide by the end of 2025; Aodong also said that it will complete the construction goal of 10,000 power stations in five years; GCL Energy plans to build 6,000 power stations during the Tenth Five-Year Plan period, serving 500,000 vehicles … …

Force standardization by scale,This bottom-up development ideaObviously, it is clearer than ten years.

Standardization is the inevitable result of power exchange, and the power exchange enterprises that entered the market early are becoming the standards themselves.Take the future as an example. Since the release of the power exchange mode, Li Bin has been releasing signals to the outside world. Wuhan Weineng gives priority to serving Weilai automobile users. However, as an open platform, it is its long-term goal for different companies to participate in the use of Wuhan Weineng’s BaaS system, and the premise of cooperation is that automobile enterprises must adopt the same battery pack specifications and standards as Weilai automobile.

Among the power exchange industry standards formulated by the National Energy Administration, Weilai took the lead in compiling three standards, namely, 10435, 10436 and 33025, and deeply participated in compiling two standards, namely, 10434 and 33004.

In addition, Geely and BAIC, the third-party operators of power exchange, Aodong and Botan Technology, and Contemporary Amperex Technology Co., Limited, the battery manufacturer, all played an important role in the formulation of national and industrial standards for power exchange.

Enterprises that change electricity early are taking the first-Mover advantage.

It took ten years for the initial answer of changing electricity and new energy vehicles to be initially applied.

However, if we look to the future, there is still more way to go before power exchange becomes the optimal solution.

On the one hand, today, the power battery has not formed a stable structure like the engine of a traditional fuel vehicle.It is still undergoing a subversive update.Today’s sodium battery, tomorrow’s hydrogen fuel cell & HELIP; …

Compared with the current unified lithium battery standard, it is more difficult to change the power at the end on a large scale.How to catch up with the pace of power battery after the popularization of high cost.

On the other hand,Power exchange puts forward higher requirements for battery capacity.. The power exchange mode has changed the one-to-one relationship between new energy vehicles and batteries. To meet the needs of a car, a battery is obviously not enough.

However, insufficient battery capacity is a major pain point in the new energy automobile industry. This year, Tucki, Weilai and other automakers have delayed delivery due to extremely tight battery supply. Under the seriously unbalanced supply, the rumor that "He Xiaopeng, chairman of Xpeng Motors, crouched at the door of Contemporary Amperex Technology Co., Limited for batteries" was once widely circulated in the industry.

In other words,The requirement of one battery per vehicle has put tremendous pressure on the upstream production capacity, not to mention the situation of more than one battery per vehicle.

Net exposure Sogou browser security vulnerability sogou response is unclear

On November 5th, a message about "Sogou browser was exposed with obvious loopholes and tens of millions of users’ privacy was leaked in batches" began to spread to major media from the Kafan Forum.

According to the news, after logging in to Sogou browser with qq account, users will be able to find thousands of user names, accounts and passwords of unfamiliar users on many websites. There are inexplicably a lot of web pages in the user’s browser favorites that the user has not stored before. After opening the corresponding favorite web pages, even the browser will automatically fill in the user name and password and conduct electronic transactions directly.

For the first time, browser security vulnerabilities leaked privacy incidents, and sogou urgently needed to give users an explanation.

Some related technicians found files such as "HistoryUrl3_base" and "FormData3.dat" in the local browser of Sogou browser, which could not obtain the corresponding information without using professional software. After the Sogou browser synchronized the user’s stored account password and the webpage in the favorites to the cloud, the synchronized data was synchronized to other users’ computers, resulting in the disclosure of a large number of users’ private data information, which will lead to a large number of users’ property losses in this vulnerability incident.

It is understood that the recent Sogou browser security breach leaked user privacy security incidents for the first time in history, and a large number of user privacy data leaked and distributed incidents caused by browser security breaches. As a historical precedent, the security vulnerability incident of Sogou browser will attract more users’ attention. sogou needs to speed up the process of fixing product vulnerabilities and give users an early account of this matter.

New sogou made a good start. The biggest impact of Sogou browser security incident was sogou search

Since the news that sogou will be acquired by 360 on May 10th this year, it has been more than four months since the news that "Tencent acquired 36.5% shares in sogou" was confirmed, and the acquisition of sogou came to an end temporarily.

On November 3rd, sogou released the unaudited financial report for the third quarter of sogou as of September 30th, 2013. According to the report, the total revenue of New sogou in the first quarter of 2013 (the first quarter after sogou was acquired by Tencent with a 36.5% stake) was US$ 57 million, up 53% year-on-year, which set a good start for the development of New sogou.

And CNZZ, a traffic statistics agency, shows in the report that sogou search occupied 12.06% of the whole domestic search market on October 26th, reaching a new high.

After the browser is the most important Internet portal, Sogou browser, as the first event that a large number of user data are leaked due to browser security vulnerabilities, will not only have a great impact on its own development. As another sogou search business that can get more data from users and is more qualified to be an Internet portal, it will probably change the rapid development of Tencent after its shareholding, resulting in a small-scale share reduction.

Therefore, the security incident of Sogou browser is not only related to the future development of Sogou browser, but also will affect the development of sogou search-based sogou. (According to the vulnerability test of Dagong. com reporter at 11: 40, the security vulnerability of Sogou browser is no longer there.)

Sogou denied that the rumor of browser security vulnerabilities was ugly. "The poster said that the account was stolen."

After the sogou browser security vulnerability incident was widely spread by the media, which attracted the attention of the industry and even the society, sogou announced yesterday that the technical team of sogou browser started to verify the authenticity of the incident as soon as possible after the "sogou browser security vulnerability" incident was reported online, and confirmed that there was no security vulnerability in sogou browser. As for the reasons for this kind of news, sogou said that its strong development momentum made some competitors launch unfair competition in the name of kidnapping users, and especially said that it would not give up protecting the ultimate rights and interests of users by legal means.

Subsequently, at around 20: 31 yesterday, the k53941 user who had previously posted "Sogou browser broke security holes" on the technical forum card meal also posted that the owner of this user ID had not used it for a long time, and this time, the behavior of repeatedly posting multiple Sogou browser vulnerability posts was caused by the hacker after the ID password was stolen.

In this regard, some netizens expressed doubts. Since this user did not log in to this ID number for several months, why did he log in to this account shortly after the security vulnerability of Sogou browser was exposed? Are there still some unknown things behind it? Can this user also expose the login record of his forum account to improve the credibility of his speech?

Previously, on the platform of Black Cloud Vulnerability, many people in the industry and outside the industry have personally witnessed the seriousness of privacy leakage in view of the privacy leakage of sogou Pinyin. At that time, the announcement given by sogou was that Bing, the search engine, did not abide by the agreement of robots.txt, but it did not claim that its team’s means of protecting the privacy of input method was not enough, and more secure verification methods should be used to protect the privacy of input method users. As a heavyweight product in the legendary three-stage rocket of sogou, sogou input method is a leading product in both PC and mobile Internet. After a product with such a huge number of users has privacy loopholes, this response has aroused the dissatisfaction of many sogou input method users, and also provided opportunities for other input method manufacturers to develop users.

This time, regardless of whether there is a security loophole in Sogou browser, we will not consider whether posting claiming that the account was stolen is a way for sogou to refute rumors. After sogou became a shareholder in Tencent, his performance did show a good development trend. In this security vulnerability incident, the third-party vulnerability platform Wuyun and 360 security guards clearly stated that in a certain period of time, the second vulnerability of Sogou browser did exist. No matter whether the vulnerability incident is an oolong incident or not, sogou should give users a more comprehensive and satisfactory explanation, and try not to blindly find ways to excuse themselves. Users know whether there is a vulnerability, and promise to provide users with a better Sogou browser, and promise that sogou can compensate those users who have really suffered economic losses from Sogou browser as long as relevant certification materials are given. Is it a better way to deal with the incident?

Text/Xiao Qian, Weibo Xiao Moqian, WeChat net1996

CCTV Drama Review: I gave "Casting Sword in Desperate Situation" five stars!

  CCTV News:On the occasion of the 90th anniversary of Gutian Conference, the revolutionary historical TV series "Casting Sword in Desperate Situation" jointly produced by CCTV, Huace Film and Television and Xiamen Wansheng Film and Television landed on a set of prime-time hits of CCTV. This is an unforgettable history, and in all fairness, it is a meticulous work.

  As the ancient poem goes, "When we look at the side of the ridge, the distance is different", when we choose different angles and different criticism methods to treat the same TV play, the connotation, value and significance we can see are also very different. Generally speaking, there are political, economic, moral and cultural standards for judging the value of TV works. Among them, the "ratings" standard once became an important indicator.

  Over the years, CCTV has been practicing the "ratings" standard and establishing the "ecological" standard in TV evaluation. The connotation of "ecology", from nature to humanity, is very rich. In short, it is to advocate the optimization of TV ecology, advocate the "green" and "environmental protection" of TV, and create a good humanistic and social environment, which is ultimately consistent with the goal of building an ecological and civilized society advocated by the country at present.

  By introducing the concept of "ecology" to re-examine TV, we will gain a brand-new understanding of TV. By the standard of "ecology", I give "Casting Sword in Despair" five stars.

  The first star: to show the "diversity" of TV cultural ecology.

  Protecting biodiversity and maintaining ecological balance are the core concepts of ecology. As far as the healthy development of TV ecology is concerned, it is also very important to pay attention to the wide coverage of TV drama content and theme categories, avoid certain types of "prevailing" and "homogenization", and pay attention to the richness of ecological categories. For decades, China TV plays have fully demonstrated the "diversity" development trend of TV cultural ecology. Especially since 2010, the creation of TV dramas on revolutionary history has reproduced the glorious course of China revolution and painted a magnificent film and television art scroll of China revolutionary history with unique theme advantages, grand historical perspective, lofty value guidance and magnificent aesthetic character. It is a necessary complement to the previous spring tide in Europe, America, Japan and South Korea, as well as the craze for costume, Hong Kong and Taiwan, and the craze for realistic themes. Moreover, it is also a drama about revolutionary history. The focus of this drama is the historical events during the land reform period, which fills the gap in the theme of TV dramas in this period and enriches the ecological categories of TV dramas in China.

  The second star: highlight the influence of "environment" in ecology on people.

  A very core factor in ecological research is the research environment, including the influence of natural environment and human environment on people. Casting Sword in Despair is adapted from a real historical event that began in 1928. It is a past story that was born in a real history and region. It is 90 years apart from the present time and space, and it may become a fading historical memory. The value of this film lies in the efforts made by the creators to restore various historical scenes in their artistic creation, and the "handwriting" in scene selection and production restoration is amazing. Gutian site, Woods behind Gutian site, Peitian ancient village, uninhabited village, Dingwuling, Quaoli pier, Xiaozong ancestral hall and many other landmark buildings with historical features and regional characteristics are presented on the screen one by one. Pulling the audience back to the hard revolutionary years in an instant not only restores history, but also brings it to life, which is very different from the fabrication of some current time-travel dramas.

  Moreover, the characterization, character and environment in the play have formed a special relationship, especially "restoring the texture of the times" and highlighting all kinds of "conflicts" and "growth" of the characters in the ever-changing environment. This kind of "ecological" observation has broken the facebook and conceptual characterization mode, making the characters in the play more real, lovely, full of flesh and blood and touching people’s hearts. Specifically, its special "environment" lies in "the desperate situation of guerrilla warfare for three years", its core "conflict" lies in "overcoming all kinds of non-proletarian thoughts", and its special "growth" lies in the fact that it has finally grown from "a Red Army team dominated by peasants at the beginning and with complex components" to "a red iron army with firm faith and fearlessness".

  The third star respects the "naturalness" in the ecology.

  This naturalness is highlighted in the realism of "natural carving" in characterization. Judging from the drama about revolutionary history, the TV series "Casting Sword in Desperate Situation" is very "grounded" and its characters are very real and lovely. The expression of history is not rigid, not conceptual, respecting history, respecting the weakness of human nature, and not making things up. The appeal of art comes from "truthfulness". No matter whether it is the main character or the minor character, its various real and meticulous performances have a moving power. What is the true face of a team with mixed components, mainly farmers, lax discipline, unclear beliefs and scattered sand? This is one of the highlights of this drama, and it is also a place where many comedies are highlighted (for example, because sausage forgot the gun, because pork forgot to return to the team, etc.).

  Another example is the shaping of the main characters, especially Chairman Mao, who suffered from malaria because of acclimatization. There is a voice-over in the play: "The leader who led the people of China to overthrow the old world and establish a new China was also in such an embarrassing situation, which is enough to show how hard-won our socialist country is now!" There are many aspects in the film about Zhu Mao’s Red Army’s use of soldiers as gods, but this passage has broken the way of "deifying" the leaders and really has a convincing force.

  The fourth star attaches importance to the "spiritual ecology" of the characters.

  Literature and art are the project of casting the soul. General Secretary of the Supreme Leader emphasized that patriotism should be the main theme of literary and artistic creation, and people should be guided to establish and adhere to the correct views on history, nationality, country and culture, so as to enhance their backbone and confidence in being Chinese. The influence of TV series on people’s spirit is very profound, because the visual expression of TV series can easily lead to idol effect. Looking back at the TV series "Casting Sword in Despair", if we use the "ecological" standard to measure it, it is very necessary to educate people like "Do not forget your initiative mind". The independent camp in western Fujian led by Li Huacheng forged the soul of the army in the desperate situation of "no food, no bullets, no medicine", adhered to the principle of "building the party ideologically and building the army politically" established by Gutian Conference, and made concerted efforts with Chen Tianyou and other team leaders. Cruel war scenes, firm revolutionary beliefs, and the sacrifices and growth of all the soldiers have moved countless netizens: "It is really not easy to pay such a painful price behind a few strokes in history books!" "Suddenly understand us ‘ Listen to the party’s command, win the battle, and have a good style of work ’ How did the people’s army grow up! "

  The fifth star: the ecological "integrity" of the team of editors and directors.

  The attributes of TV series are complicated, which are both works of art and cultural products. Its concrete formation has its own unique cultural and ecological environment, and it is also in a unique ecological chain. Very different from traditional works of art, it is first of all the product of "team" wisdom. It is an art science, and it must be operated scientifically as a whole. From planning, scriptwriting, filming to being on the screen, it must go through a strict production process, and it must be a harmonious and optimized combination of creative factors such as screenwriter, director, actor, camera shooting, recording, art design, music, makeup, clothing and props. The so-called "amateurs watch the excitement, experts watch the doorway". If you look at the TV series "Casting Sword in Despair" from a professional perspective, you can see its "step by step" exquisiteness.

  On the one hand, this "high-quality" ecological optimization combination is based on the improvement of the professional level of China’s TV drama creation, on the other hand, it is based on the superior combination of its own creative team. In 2016, "The Desperate Defender" triggered a ratings boom, and won many awards such as "Five One Project Award", "Flying Award" and "Golden Eagle Award". As the second part of the "Three Musts" series, Casting Sword in Despair is still under the general planning of Yuan Jingui, starring Qian Linsen, a famous screenwriter, and Zhang Tong, who won the flying prize for "Breaking Defender", and adding new blood to the strength school. Affectionate patriotism, compact plot, excellent drama production, exquisite interpretation by actors, music that makes the finishing point, and many obscure behind-the-scenes creators have restored a true history for us with their professional level and dedication.

  Literature and art can’t be slaves of the market, and they can’t get lost in the tide of market economy. A good work should put social benefits first. Excellent literary and artistic works, it is best to be successful in thought and art, and to be welcomed in the market. Literature and art should be able to help build a green humanistic ecological environment and enhance the spiritual and ecological strength of the audience. Under this standard, I give "Casting Sword in Desperate Situation" five stars. It is an unforgettable historical memory, a "picture book of revolutionary heroes", and its intrinsic value, in addition to the digital display of current ratings, can also play a supplementary role in history textbooks.

  (Commentator: Zhang Wenjuan)

How to use drugs for pregnant and lactating women infected with COVID-19? The answer you want to know is here.

How to use drugs for pregnant and lactating women infected with COVID-19? The answer you want to know is here.

Haikou, December 24th   (Reporter   Marco) With the adjustment of national epidemic prevention policy, the infection rate in Covid-19 continues to rise. So how should some special people, especially pregnant and lactating women, take medicine after being infected with Covid-19, so as to effectively relieve their symptoms and protect their baby’s health? Zou Junjin, director of the clinical pharmacy department of Hainan Women and Children Medical Center, answered this question.

Zou Jun said that the Covid-19 infection rate and symptoms of pregnant women are similar to those of the general population, and most of them are asymptomatic or mild. The symptoms are similar to other acute upper respiratory tract infections, such as fever, dry throat, cough, runny nose and aches all over. Generally, they will get better in three or four days, and will gradually recover in about seven days. Therefore, if pregnant women are infected with Covid-19, they need not be too anxious. When necessary, they can use drugs under the guidance of doctor Yamatonokusushi.

one

What should pregnant women do after they are infected with Covid-19? Do you need medication?

A: In principle, there is no need for medication for asymptomatic infected people. In the early stage of the disease, we can use drugs according to the symptoms, such as antipyretic drugs for fever, cough and expectoration drugs for cough and phlegm, and there is no need to use other drugs, such as antiviral drugs and antibiotics. In addition, in the choice of medication, try to choose a single preparation and avoid using a compound preparation.

2

What drugs can be used after pregnant women are infected with Covid-19?

A: Early pregnancy is a critical period of embryo development. At this stage, drugs should be avoided as much as possible to reduce the impact on embryos. The second and third trimester of pregnancy is relatively safe, and there are many drugs to choose from. Please refer to the relevant drug instructions and the drug list issued by the National Obstetrics Professional Medical Quality Control Center.

three

Pregnant and puerperal women with basic diseases are infected with Covid-19. What suggestions do you have for medication?

A: For pregnant women who are infected with Covid-19 and have basic diseases, such as hypertension, diabetes, coronary heart disease, etc., it is best to consult a doctor or pharmacist when choosing drug treatment, and inform them of the types of drugs they have taken for a long time before, so as to avoid the interaction between drugs and the fluctuating influence on basic diseases, and not to blindly use drugs.

four

Can lactating women continue to breastfeed when they are infected with Covid-19?

A: Of course. As long as the mother’s body allows, you can continue breastfeeding, because the risk of Covid-19 transmission through breast milk is extremely low. Breast milk contains antibodies and other anti-infective factors from the mother, and the baby can be passively immune to the virus after ingestion. It should be noted that before breast-feeding and daily nursing contact with the baby, breast-feeding women need to implement protective measures, such as wearing N95 masks, washing hands frequently, ventilating frequently, cleaning and disinfecting the surface of objects touched by their mothers regularly.

Zou Jun reminded that pregnant expectant mothers should go to the hospital as soon as possible if their condition is obviously aggravated after being infected with Covid-19, such as persistent high fever, dyspnea, chest pain, abdominal pain, vaginal bleeding and abnormal fetal movement.

Cartography/Zhang Xin

Beijing launched HPV vaccination pilot for school-age girls this year.

  Recently, the Beijing Municipal Health and Health Commission, the Municipal Finance Bureau, the Municipal Medical Insurance Bureau and other nine departments jointly issued the Implementation Plan for Accelerating the Elimination of Cervical Cancer in Beijing (2023— 2030) (hereinafter referred to as the "program"). According to this plan, this year, the city will launch a pilot project of HPV vaccination for school-age girls, encourage qualified areas to actively participate, explore various channels of vaccine protection, and realize the willingness of school-age girls and women who meet the vaccination conditions.

  Piloting HPV vaccination for school-age girls

  The plan proposes that the city will achieve the goal of accelerating the elimination of cervical cancer by implementing three-level preventive measures: HPV vaccination for school-age girls, cervical cancer screening for school-age women, and treatment of patients with cervical cancer and precancerous lesions. By 2025, all districts in the city will carry out HPV vaccination services for school-age girls; The screening rate of cervical cancer in school-age women reached 50%; The treatment rate of patients with cervical cancer and precancerous lesions reached 90%. By 2030, continue to promote HPV vaccination for school-age girls; The screening rate of cervical cancer in school-age women reached 70%; The treatment rate of patients with cervical cancer and precancerous lesions reached 95%.

  In order to achieve the above goals, the city will carry out a number of key actions.

  The first is literacy promotion, advocating the idea that women are the first responsible person for their own health, and raising awareness of HPV vaccination and regular screening. At the same time, make full use of the Internet, mobile clients and other new media and traditional media, carry out all-round and multi-level social advocacy activities and public welfare publicity, and widely spread the knowledge of cervical cancer prevention and treatment.

  Followed by the HPV vaccination campaign. The plan proposes to actively organize and mobilize, give play to the role of schools in organizing and mobilizing HPV vaccination for school-age girls, and carry out publicity and registration to enhance the willingness of school-age girls to vaccinate HPV. In addition, strengthen the standardized management of vaccination, timely announce qualified and qualified vaccination units, realize the traceability of the whole vaccination process, and give priority to ensuring the vaccine supply for school-age girls. Gradually realize the coverage of the whole city. In 2023, we will launch a pilot project of HPV vaccination for school-age girls, encourage qualified areas to actively participate, explore various channels of vaccine protection, and realize the willingness of school-age girls and women who meet the vaccination conditions.

  Expand the coverage of free screening for cervical cancer

  In terms of cervical cancer screening action, the plan proposes that the city will expand the coverage of free cervical cancer screening. Expand the coverage of free screening for school-age women in the city to the permanent population, and improve the screening rate of cervical cancer among school-age women. Set up and publish screening outlets reasonably, and promote the appointment screening system to facilitate women to receive screening nearby. School-age women who are willing to participate in the screening can participate in the screening in qualified institutions in the city’s domicile or permanent residence. Optimize the free screening process for cervical cancer. The initial screening uses human papillomavirus nucleic acid detection, and those with abnormal screening results are examined by cervical cytology, colposcopy and histopathology.

  The cervical cancer screening service for female workers will continue to be strengthened, and employers will be guided to implement the Law on the Protection of Women’s Rights and Interests and the Provisions on Health Care for Female Workers, select appropriate screening programs and conduct cervical cancer screening on a regular basis. Strengthen the public welfare cervical cancer screening service for female employees in difficult enterprises and new employment forms. Give full play to the role of trade union workers in mutual assistance and actively carry out care and assistance work. Increase the praise and encouragement to employers who protect the health rights and interests of female employees according to law.

  Multi-departments work together to reduce the burden of patients seeking medical treatment

  In terms of treatment and safeguard actions, the plan proposes that the city should promote the application of unified and standardized guidelines for the diagnosis and treatment of cervical cancer, promote the management of clinical pathways, and do a good job in the treatment of cervical cancer patients. Explore a new model of integrated prevention and control. Improve the cervical cancer prevention and control network, and actively promote the integrated services of HPV vaccination, cervical cancer screening, diagnosis and treatment. Give full play to the advantages and functions of traditional Chinese medicine in the prevention and treatment of cervical cancer, and explore a new mode of prevention and treatment of integrated traditional Chinese and western medicine.

  At the same time, improve the medical security system. Improve the multi-level medical security system with basic medical insurance as the main body, medical assistance as the backing, supplementary medical insurance, commercial health insurance, charitable donations, medical mutual assistance and other common development, and work together to reduce the medical burden of cervical cancer patients. The city will also improve the humanistic services for people with cancer. Improve rehabilitation guidance, pain management, nursing and nutrition, psychological support and other supporting measures to improve the survival rate and quality of life of patients with cervical cancer.

  In addition, the city will actively promote appropriate technologies for cervical cancer screening and diagnosis and treatment, and explore the use of new technologies such as the Internet and artificial intelligence to optimize screening and diagnosis and treatment service processes. Use telemedicine technology platforms such as "cloud women and children" to improve the management and service level at the grassroots level.

  Text/reporter Jiang Ruojing

All localities should create all elements of the whole agricultural industry chain in all directions and promote the deep integration of industries.

  CCTV News:The reporter learned from the Ministry of Agriculture and Rural Affairs on September 6 that the processing of agricultural products has become an important fulcrum for the development of rural industries. In 2022, there were 90,000 agricultural products processing enterprises above designated size, with operating income exceeding 19 trillion yuan.

  China actively expands the multiple functions of agriculture, taps the multiple values of rural areas, and promotes the integrated development of primary, secondary and tertiary industries. A total of 180 industrial clusters with advantages and characteristics, 300 modern agricultural industrial parks and 1,509 strong agricultural towns have been built nationwide, and 1,952 national key leading enterprises have been identified.

  In 2022, there were 90,000 agricultural products processing enterprises above designated size, with operating income exceeding 19 trillion yuan. In the future, all localities will focus on rural key industries and characteristic industries, upgrade the agricultural product processing industry in all links, promote rural characteristic industries in all chains, cultivate industrial management entities in all fields, promote deep integration of industries with all factors, build an all-round agricultural industrial chain, and take multiple measures to promote the high-quality development of rural industries led by agricultural product processing.

Behind Article 20′ s seven consecutive box office titles in a single day is the people’s desire for fairness and justice.

Author: film and television weather vane

In the first week after the Spring Festival holiday (from February 19th to February 25th), the film market in China mainland continued its strong box office trend in the post-Spring Festival period, with the box office closing at 1.922 billion yuan that week. Among them, Article 20 earned 588 million yuan and won the box office for seven consecutive days. Pegasus 2 followed closely with 533 million yuan.

Under the unfavorable situation that the box office of Article 20 is only half that of YOLO during the Spring Festival holiday and only ranks fourth in the box office of the Spring Festival file, it can achieve a big counterattack of winning the championship for seven consecutive days in a single day, mainly because it satisfies the people’s desire for fairness and justice, arouses the emotional resonance of the audience, and has great practical significance.

Last week was the first week after this year’s Spring Festival holiday. After the Spring Festival box office blowout, the box office in China mainland declined, but it remained at a high level. According to the data of Cat’s Eye Professional Edition, the box office closed at 1.922 billion yuan that week, with 43.298 million people watching movies and 2.92 million screenings.

During the 8-day Spring Festival holiday, the box office of Article 20 was only half that of YOLO, ranking fourth in the Spring Festival box office. However, with the continuous fermentation of good reputation, the attendance rate of this film continued to rise in the second half of the Spring Festival holiday. After the holiday, on February 19th, the film won the first prize in a single-day box office when it was behind schedule, and then a wave of single-day box office champions for seven consecutive days made the film the biggest winner in the "post-Spring Festival file".

The box office of Article 20 can achieve a super counterattack, mainly because of its good reputation. As a propositional composition-style film for popularizing the law, director Zhang Yimou skillfully combines comedy, family, crime, tragedy, law and other types and elements instead of preaching with a straight face. The three cases are connected together through prosecutor Han Ming played by Lei Jiayin, which makes the film not only enjoyable, but also touching people’s hearts and satisfying people’s desire for fairness and justice, which is of great social practical significance.

Pegasus 2, a comedy about racing directed by Han Han, got 533 million yuan at the box office last week, ranking second in the weekly box office list, with a cumulative box office of 3.064 billion yuan, and also ranked second in the Spring Festival file.

The box office and word-of-mouth of "Pegasus 2" greatly surpassed the first film released in 2019, which fully demonstrated the audience’s love for this film. After the word-of-mouth failure at the box office of Four Seas in the Spring Festival of 2022, director Han Han was brave after knowing shame, and made a family fun racing movie for the audience with a creative attitude of Excellence, completely following the narrative and expression techniques of commercial films.

This year’s Spring Festival file is short of The Wandering Earth and Operation Red Sea’s "Feng Shen I", a visual blockbuster that represents the level of China’s film industry. The racing scene in the second half of "Pegasus 2" is thrilling and soul-stirring, and great efforts have been made in shooting and production, which makes up for this regret, which is also an important reason for the film’s good box office reputation.

Last week, the mainland film market in China entered the "post-Spring Festival". On February 23rd and 24th, there were four new Chinese and foreign films, such as argyle Secret Agent and Still Think You Are the Best 2, respectively, but the box office performance was average, especially Still Think You Are the Best 2, which was far less than the first one.

On the other hand, he thinks: "The Spring Festival file only has seven days off, so there are more than twenty days in the first month. If we can promote the emergence of a’ post-Spring Festival file’, it should be a good thing for the China film market. I hope to alleviate the problem of uneven hot and cold in the film market to a certain extent. "

According to Rao Shuguang’s definition, this year’s "post-Spring Festival" is from February 18th to March 9th (the 29th of the first month). In addition to the four new films released last week, there will be 13 new films released at home and abroad. Which film is expected to continue the market popularity?

However, this year’s "post-Spring Festival" is still full of stamina because of Article 20 and Pegasus 2, and Hollywood blockbusters like Dune 2 may not be able to get cheap in the competition. It is the best result for everyone to make the market cake bigger.

According to the China Film News, Rao Shuguang said: "It is not only the post-Spring Festival file, but we are used to thinking that in the blank period or the low period of watching movies, we need to deeply study and create film works suitable for a certain period, so as to make the film market trend more balanced and orderly throughout the year, and it can also effectively cultivate the consumption habits of the audience and increase the frequency of watching movies."

As President Rao Shuguang said, the film market in China is still too dependent on the Spring Festival, summer vacation, National Day, May Day, New Year’s Day and other major holidays. If the box office potential of off-season and weekend stalls can be better explored, the film market in China will be more prosperous.

AI juvenile chuangguan hard technology

  Original title: AI juvenile hard technology

  In March, 2023, a ranking released by Zeta Alpha, an American industry research institution, made many domestic artificial intelligence (AI) practitioners feel very excited. Among the top 100 cited AI papers in the world, China’s Defiance Technology, a unicorn enterprise founded by three Tsinghua "Yao Ban" students, ranked second only to the "popular star" of international artificial intelligence.

  As early as before the artificial intelligence surge, they embarked on the journey of sending artificial intelligence technology from the laboratory to real life, and finally let China’s artificial intelligence industry stand on the world-class track.

AI juvenile chuangguan hard technology

  Xueba juvenile "assembly number"

  Where can I see the most Olympic gold medal winners in China? The answer may be-Defiance Science and Technology Research Institute of Jinyu Zhizao Workshop in Haidian District. Among the 500 researchers, there are more than 30 former gold medal winners of the International Informatics Olympiad, the acm international collegiate programming contest and the National Youth Informatics Olympiad.

  The leader of the research institute is Yinqi. Inki, an 18-year-old boy, was admitted to Tsinghua University in 2006. After entering the school, he was selected to enter "Yao Ban".

  "Half the talents in Tsinghua, half the talents in Tsinghua are in Yao Ban" —— Yao Ban, which won such praise from the outside world, is the computer science experimental class of Tsinghua School, founded by Academician Yao Qizhi, an American Turing Award winner and a world-famous computer scientist.

  "World-class computer professionals must explore the most cutting-edge issues of global science and technology." In the class of "Yao Ban", Yinqi buried his life ambition to pursue cutting-edge technology diligently, and also met like-minded classmates Tang Wenbin and Yang Mu.

  At that time, technological change was driving "the potential of starting a prairie fire" with "a spark" on the other side of the ocean. Facebook created by Zuckerberg has changed the traditional social model in the world, and Apple led by Jobs has launched the epoch-making electronic product iPhone.

  Change is opportunity. In 2011, three Tsinghua "Xueba" jointly founded Defiance Technology, becoming the earliest artificial intelligence startup company in China. However, AI’s extremely attractive technical vision cannot directly bring the future to the front. Young geeks who are full of blood just broke into the society and were splashed with cold water. "Where is a technology startup company in China?" An investor left a word to Inch and Tang Wenbin, and the tone was beyond doubt.

  The stereotype of investors was faced by China science and technology entrepreneurs more than ten years ago. At that time, most of the capital’s eager eyes on entrepreneurial projects focused on mobile Internet applications and business model innovation that could become popular overnight. There are few precedents for the success of technology entrepreneurship, and as for artificial intelligence, few people care.

  Despite this, several young people firmly believe in their own judgment-mastering the underlying technology, they will embrace the "BRIC" that will shine sooner or later.

  Yinqi and the team worked around the clock to train the visual recognition cloud platform with a billion-level algorithm every day through the "neuron-like deep learning algorithm" to accelerate the self-repair of the platform. Just like sea tactics, the more data systematically analyzed, the more accurate the calculation and identification results will be.

  Only one year later, the false recognition rate of the contemptuous visual service platform Face++ has dropped to one in ten thousand, which is equivalent to growing into an 18-year-old adult’s brain in three years in the direction of visual recognition. By the second half of 2014, its recognition rate has reached 97.27%, and it has won the champion of three international evaluations, namely FDDB, 300-W and LFW, exceeding the recognition rate of Facebook of 97.25%. This is the catch-up of latecomers.

  Patiently cross the "Death Valley"

  In March 2016, Google’s artificial intelligence Go software AlphaGo beat the former world Go champion Li Shishi, and artificial intelligence became a household name overnight. Startups based on artificial intelligence technology have suddenly become hot. In 2017, Defiance Technology received $460 million in Series C financing.

  However, the growing pains also follow-more players, more expensive research and development, but less technology.

  Yinqi realized that after the early honeymoon period, the industry was entering the deep water area. The application of artificial intelligence technology will be the first to mature in the enterprise market, and the key battle for artificial intelligence start-ups to cross the "Valley of Death" will also start on this "battlefield". Attack the enterprise market!

  However, compared with the consumer market with high outbreak and high growth, the enterprise market is a "bitter" business. No matter in the fields of finance, security or supply chain, every industry is occupied by giants who have been deeply cultivated for many years. For a group of young geeks, it is not easy to gnaw such "hard bones".

  Shortly after entering the security industry, Tang Wenbin, as the company’s chief technology officer, found that many face recognition systems obtain information from the video shot by the front-end ordinary camera and then identify it, so it is difficult to store and transmit the video. "Why not directly make a smart cameras that can be identified immediately? It must be very valuable. "

  Just do it. A high-end smart cameras comes out, which is not only equipped with a self-developed intelligent identification system, but also uses a sensor with leading performance, an expensive processor and even a seven-color shell.

  However, when communicating with users, the team found that these products, which are cool enough in terms of technical indicators and appearance, did not meet the demand. Customers in an industry require power consumption within 3 watts, while their smart cameras consume nearly 18 watts. The cost of a piece of equipment of 10,000 yuan was even more unacceptable in the market environment at that time.

  "Looking for nails with a hammer." This experience is a detour that many companies that started with technology have gone through. On the long March of technological entrepreneurship, there is never a shortcut, and the only way is to keep going.

  Go to the nearest line of demand-

  Standing in an e-commerce platform warehouse with a temperature of minus 10℃ and an area of 20,000 square meters, Tang Wenbin and Yinqi found that any air conditioner and heating can’t play any role here. In this environment, the total walking distance of the picking team can reach 30 to 40 kilometers at the end of the day. Is there any way to improve the efficiency of warehousing and logistics? Since then, in this large warehouse, more than 500 robots of three types of partners have been ignored and worked together, which has improved the efficiency of personnel by 40%.

  Go to the "battlefield" where the demand for technology is the most urgent-

  At the beginning of 2020, the epidemic broke out in COVID-19, and the emergency project team headed by Yinqi was set up on the first day of New Year’s Day. More than 100 people joined the research and development of artificial intelligence temperature measurement scheme. Ten days later, Ming Ji AI intelligent temperature measuring system was officially delivered for trial operation, and it was applied to Beijing’s major subways, supermarkets, hospitals and other scenes.

  Nowadays, in more than 100 domestic cities, more than 10 countries and regions, ignoring urban Internet of Things solutions is always exerting wisdom for urban operation; In the smart warehouses of major enterprises, the smart pallet four-way car with small body and standard load of 1500 kg has been put into battle; Hundreds of millions of smart phones around the world have used the contemptuous device unlocking and computational photography solutions …

  The technical vision of "using artificial intelligence to benefit the public" of young geeks 12 years ago has blossomed in fields, factories, mines, schools and communities.

  Embrace the wave of hard technology entrepreneurship

  An armored robot gradually learned human actions, language, creativity and even emotions in the process of long-term contact with human beings, and was finally recognized by human beings and integrated into human society. The science fiction film Machine Butler released in 1999 showed people the future life of robots and human beings. The intelligent and warm robots in the film are now accelerating into reality.

  Yinqi said with emotion: "Technological changes will definitely roll forward, whether you join or not. If it can’t lead in core technology, China’s AI enterprises will gradually lose their position in global competition. "

  On the road of technological exploration, he is not alone with contempt.

  In 2014, Dai Wenyuan, who won the world championship in the ACM acm international collegiate programming contest, known as the "Computer Olympics Competition", and his mentor Professor Yang Qiang established the fourth paradigm. In 2016, Lou Tiancheng, who graduated from "Yao Ban" like Yinqi and was called "the leader of the building" by Tsinghua students because of his superior programming ability, and Peng Jun set up an autonomous driving company Xiaoma Zhixing. In the same year, Chen Tianshi and Chen Yunji, two brothers who graduated from the junior class of the University of Science and Technology of China, founded the CAMBRIAN artificial intelligence chip company.

  Yinqi, Chen Tianshi, Lou Tiancheng, Dai Wenyuan … In Beijing, the new generation of entrepreneurs and entrepreneurs have emerged, and the wave of hard technology represented by artificial intelligence has also swept across the country with Beijing as the center. At present, Beijing, which has gathered nearly 30% of artificial intelligence enterprises in the country, has become a veritable "AI first city".

  The innovation spiral of hard technology touches more than artificial intelligence. Relevant persons in charge of the Municipal Science and Technology Commission and Zhongguancun Management Committee observed that in the fields of high-tech and cutting-edge technologies such as new materials, virtual reality, artificial intelligence and precision medical care, a large number of technology entrepreneurs emerged, and a number of entrepreneurial enterprises with extremely high technological competitiveness and wide market application prospects rose strongly. On the road of exploring the mystery of the frontier of science and technology, the new generation of entrepreneurs will have more and more colleagues.

  Beijing becomes the first city of AI.

  By October 2022, there were 1,048 artificial intelligence core enterprises in Beijing, accounting for 29% of the total number of artificial intelligence enterprises in China, ranking first in the country, and more than 30 artificial intelligence unicorn enterprises have been born.

  Twenty-four enterprises in China have been approved to build a new generation of national artificial intelligence open innovation platform, of which 10 enterprises are headquartered in Beijing.

  There are more than 40,000 core technical talents in the field of artificial intelligence in Beijing, accounting for 60% of the country; The number of artificial intelligence papers published ranks first in the country; Among the top 100 institutions in the world in terms of the number of patents granted, there are 30 Beijing-based institutions.

  The two major industries, medical health and information technology, are becoming the "twin engines" of Beijing’s sophisticated economy under the cross-integration of artificial intelligence platform technology. In 2022, the related output value of Beijing artificial intelligence industry is estimated to be about 227 billion yuan.

  Hard technology is written into the five-year plan

  On March 12, 2021, the 14th Five-Year Plan for National Economic and Social Development and the Outline of Long-term Goals in 2035 was officially released, in which it was specifically mentioned that it was necessary to enhance the characteristics of "hard technology" in science and technology innovation board and enhance the function of Growth Enterprise Market in serving growth-oriented innovative and entrepreneurial enterprises.

  In November, 2021, the Plan for the Construction of Beijing International Science and Technology Innovation Center during the Tenth Five-Year Plan period also proposed to carry out pilot projects of equity investment and venture capital share transfer in depth to guide early investment, hard technology investment and long-term investment; Support the development of market-oriented and specialized hard technology incubators, promote the verification and maturation of scientific and technological achievements, and quickly realize transformation and industrialization.

  Hard technology refers to the key core technology that needs long-term R&D investment, has a high technical threshold, is difficult to be copied and imitated, and has a significant supporting role for economic and social development. Hard technology is at the high end of the global value chain, which has the characteristics of high intellectual property barriers, high capital investment, high information intensity, high added value of products and high industrial control, and is an important symbol to measure a country’s core competitiveness. At present, the representative fields of hard technology include photoelectric chips, artificial intelligence, aerospace, biotechnology, information technology, new materials, new energy, intelligent manufacturing and so on.(Sun Qiru)

A never-ending epidemic war: 70 years of infectious disease prevention and control in China.

  Throughout history, infectious diseases have accompanied the process of human civilization and have had a profound impact on human civilization. It can be said that the history of mankind is the history of fighting infectious diseases. As William McNeill mentioned in his book Plague and Man: "Intelligence, knowledge and organization can’t change people’s vulnerability and helplessness in the face of parasitic invasion. Since the appearance of human beings, infectious diseases have followed, and when human beings still exist, infectious diseases will exist. Infectious diseases used to be, and will certainly be, one of the most basic determinants affecting human history. "

  Since the founding of New China 70 years ago, China has made remarkable achievements in economic, social, scientific and technological fields. Among them, experts and scholars in the fields of infectious diseases and parasitic diseases in China have made outstanding contributions to the prevention and control of infectious diseases and the improvement of people’s health. In 2018, CCTV’s "Go Around China" column produced the documentary "Never Stop Epidemic War", which recorded the wars between medical and health personnel and infectious diseases in China.

  Here, we invite Professor Wang Guiqiang, the current chairman of the Infectious Diseases Branch of the Chinese Medical Association and the director of the Infectious Diseases Department of the First Hospital of Peking University, to sort out those things in the field of infectious diseases in China in the past 70 years. Those people … …

  At the beginning of the founding of New China, infectious diseases such as smallpox, plague, cholera, schistosomiasis and kala-azar were rampant in China, seriously endangering people’s health. The China Municipal Government attaches great importance to the prevention and control of infectious diseases, and has successively issued a series of principles and policies to organize national efforts to prevent and control infectious diseases. In 1980s, with the classical infectious diseases being gradually controlled, the diagnosis and treatment of viral hepatitis and liver disease became the main work of infectious diseases doctors. From the 1990s to the early 21st century, with the inclusion of hepatitis B vaccination in planned immunization and the popularization of various antiviral treatments, the infectious diseases department began to return to the essence of big infection, and the focus of its work gradually shifted from the diagnosis and treatment of viral hepatitis and liver disease to the construction of big infection discipline focusing on the improvement of the diagnosis and treatment ability of bacteria and fungi.

  First, the classic achievements:

  These achievements are worth remembering.

  (1) Eradication of smallpox

  Smallpox is a severe infectious disease caused by smallpox virus, with a mortality rate as high as 25%. As early as the 10th century, China invented human pox vaccination. In 1688, Russia sent doctors to Beijing to study human pox vaccination, and human pox vaccination began to spread all over the world. Human pox vaccination has protected many people’s lives, but the vaccinated people still have a mortality rate of 2%. In 1796, edward Cenna, a British doctor, successfully vaccinated an 8-year-old boy with vaccinia, which ushered in a new era of vaccination against smallpox.

  From January to August, 1950, there were 44,211 cases of smallpox in China, which were distributed all over the country. In that year, 7,765 people died of smallpox. In order to eliminate smallpox, in October 1950, the Central People’s Government issued the "Instructions on Launching Autumn Vaccination Campaign" issued by Premier Zhou Enlai, and made a decision to promote universal vaccination throughout the country. Subsequently, the Ministry of Health promulgated the "Interim Measures for Vaccination" to promote free vaccination in the whole country.

  In 1950, the vaccination rate of smallpox in Beijing reached 80%, making it the first city in China to eliminate smallpox. By 1952, more than 500 million people had been vaccinated against vaccinia all over the country. By 1958, the number of smallpox cases in China had dropped sharply to more than 300.

  In the spring of 1959, six people brought smallpox from Myanmar to Danjia Dazhai, Danjia District, Cangyuan County, Yunnan Province. Subsequently, two people brought smallpox to Cangyuan County, Yunnan Province from abroad. This time, the smallpox epidemic caused 672 people to get sick and 96 people died. This is the last outbreak of smallpox in China. With the recovery of the last case of smallpox in China in 1961, there was no case of smallpox in China.

  In 1966, WHO decided to launch a global smallpox eradication campaign at the 19th World Health Assembly, and adopted a resolution to eradicate smallpox. On October 26th, 1977, the last smallpox patient in the world, Somali cook Ali Mao Martin, was cured. On May 8, 1980, WHO announced at the 33rd World Health Assembly held in Nairobi, Kenya, that smallpox, which had been harmful to human beings for thousands of years, had been eradicated. Since then, the global vaccination has stopped. Smallpox was eliminated in China more than ten years earlier than that in the world.

  (2) Prevention and control of schistosomiasis

  Schistosomiasis japonica has a history of more than 2100 years in China, and it is a zoonotic parasitic disease that seriously harms human health and social and economic development. In the early days of the founding of New China, schistosomiasis was prevalent in 370 counties (cities) in 12 provinces, municipalities and autonomous regions in southern China, with a total of 11.6 million infected people, an area of 14.8 billion square meters of snails and a threatened population of more than 100 million.

  From the founding of New China to the early 1970s, comprehensive measures were mainly taken in China, including snail control and treatment with antimony potassium tartrate. Although the breeding grounds of snails were significantly reduced and the number of infected people decreased significantly, schistosomiasis was not eliminated, and antimony potassium tartrate had a long course of treatment and was highly toxic to the heart and liver. In the mid-1970s, praziquantel, a highly effective and low toxic therapeutic drug, came out, which greatly improved the prevention and control of schistosomiasis, and greatly reduced the prevalence and morbidity. Since 1990s, the strategy of schistosomiasis control in China has been adjusted to take praziquantel and health education for a large number of people.

  Prevention and control of schistosomiasis is a long-term project. In 2001, WHO thought that the overall strategy of global schistosomiasis control was to reduce the harm of the disease rather than eliminate it, but it regarded schistosomiasis as a disease that could be partially eliminated. Through the comprehensive prevention and control measures focusing on the control of infectious sources, and the Outline of the National Medium and Long-term Plan for the Prevention and Control of Schistosomiasis (2004— The effective implementation of "2015)" has effectively promoted the process of schistosomiasis elimination in China. In 2008, the country reached the standard of schistosomiasis epidemic control, and in 2015, it reached the standard of schistosomiasis transmission control. Since then, the prevention and control of schistosomiasis in China has moved towards transmission blocking and even elimination.

  After 2016, the endemic areas of schistosomiasis in China will continue to adhere to the working principle of "prevention first, treating both the symptoms and root causes, classified guidance, comprehensive management, joint prevention and control", implement comprehensive prevention and control strategies based on the control of infectious sources according to local conditions, and strive to achieve the 2020 goal set in the 13 th Five-Year National Schistosomiasis Prevention and Control Plan — — By the end of 2020, 96.5% of schistosomiasis endemic counties (cities, districts) in China have reached the standard of transmission interruption or elimination, among which more than 75% of endemic counties (cities, districts) have reached the standard of elimination, and all endemic counties (cities, districts) in China have reached the standard of "Healthy China 2030".

  (3) Prevention and treatment of tuberculosis

  Tuberculosis is a chronic infectious disease with the longest history and the largest number of deaths. Before the invention of anti-tuberculosis drugs such as streptomycin in the 1940s, tuberculosis was almost incurable.

  As early as 1933, China established the China Tuberculosis Association and opened tuberculosis clinics in some cities. In 1937, the Tuberculosis Branch of Chinese Medical Association was established. In 1949, there were 12 prevention and treatment institutions in China, with more than 600 beds, 29 X-ray machines and 120 medical staff specializing in tuberculosis prevention. At that time, the prevalence rate of tuberculosis in China was as high as 17.5 million/100,000, and the mortality rate was 2 million/100,000.

  After the founding of New China, the Central Institute of Tuberculosis Prevention and Control and the BCG Promotion Committee were successively established in Beijing. Tuberculosis prevention institutions at all levels have been gradually enriched and developed. By the mid-1960s, the morbidity and mortality of tuberculosis in big cities such as Beijing and Shanghai had dropped to the same level as that in Japan. The results of the first national tuberculosis epidemiological sampling survey in 1979 showed that the prevalence rate of active tuberculosis in China was 7.17/100,000, and the prevalence rate of smear-positive tuberculosis was 1.87/100,000, which was significantly lower than that in 1949.

  Since 1981, the state has formulated and implemented three national ten-year plans for tuberculosis prevention and control. In January 2005, the tuberculosis management information system was launched. In 2011, the General Office of the State Council issued the National Tuberculosis Prevention and Control Plan (2011— 2015). In 2013, the former Ministry of Health issued the Management Measures for Tuberculosis Prevention and Control.

  In recent years, the rising trend of tuberculosis epidemic in China has been effectively curbed, and the prevention and treatment of tuberculosis has made remarkable achievements. The fifth national tuberculosis epidemiological sampling survey in 2010 showed that the prevalence rate of active tuberculosis in China was 4.59/100,000, of which the prevalence rate of infectious tuberculosis was 66/100,000, which was 64% lower than that in 1979.

  (D) Hepatitis B vaccination into the national immunization program.

  China is a high epidemic area of hepatitis B. The second national hepatitis B serological survey in 1992 showed that the positive rate of HBsAg was 9.75%.

  In the early 1990s, Professor Tian Gengshan and Academician Zhuang Hui made suggestions to the country, emphasizing the importance of hepatitis B vaccination. In 1992, the former Ministry of Health formally brought hepatitis B vaccination into the planned immunization management, and at the same time promulgated the National Hepatitis B Vaccination Implementation Plan. In 2002, hepatitis B vaccine was included in the national immunization plan, and newborns were provided with hepatitis B vaccine free of charge, and newborns were required to be vaccinated within 24 hours after birth.

  In 2006, in order to evaluate the effect of incorporating hepatitis B vaccine into the national immunization program, the former Ministry of Health organized a national hepatitis B seroepidemiological survey. The results showed that the HBsAg positive rate of children at birth decreased from 9.67% in 1992 to 0.96% in 2005, a decrease of 90%. In May 2012, China achieved the goal of controlling the HBsAg carrying rate of children under 5 years old to below 2% through the verification of WHO Western Pacific Region, and achieved the goal of controlling the HBsAg carrying rate of children under 5 years old to below 1% by 2017 ahead of schedule.

  In recent years, the vaccination rate of neonatal hepatitis B vaccine in China has remained above 95%, and the infection rate of children has decreased significantly year by year. In 2014, the fourth national hepatitis B serological survey showed that the HBsAg positive rate of children aged 1-4 years in China was 0.3%, which was over 60% lower than that in 2006.

  (5) Prevention and treatment of viral hepatitis and liver disease

  The development of viral hepatitis and liver disease in recent years is inseparable from the dedication of a large number of experts in infectious diseases in China.

  In 2000, at the National Viral Hepatitis Conference held in Xi ‘an, Professor Si Chongwen, Chairman of the Sixth Committee of Infectious Diseases Branch of Chinese Medical Association, led the updating of the Viral Hepatitis Prevention and Control Program. In 2005, Professor Weng Xinhua, Chairman of the Seventh Committee of Infectious Diseases Branch of Chinese Medical Association, and Academician Zhuang Hui, Chairman of Hepatology Branch of Chinese Medical Association, jointly compiled and published the Guidelines for Prevention and Treatment of Chronic Hepatitis B and Hepatitis C.. The publication of these two guidelines has made positive contributions to the prevention and treatment of viral hepatitis in China and guided the clinical practice in the whole country. Since then, the guidelines have been updated successively in 2010 and 2015, and the fourth edition of Guidelines for the Prevention and Treatment of Chronic Hepatitis B and Guidelines for the Prevention and Treatment of Hepatitis C are currently being updated.

  1. Hepatitis A

  Hepatitis A is a worldwide public health problem caused by hepatitis A virus (HAV) infection, which is mainly transmitted through fecal-oral route. Its prevalence is closely related to social and economic development, living habits, sanitary conditions and vaccination. In 1988, the world’s largest outbreak of hepatitis A occurred in Shanghai, with more than 300,000 people infected. With the rapid development of China’s economy and the improvement of people’s living conditions, hepatitis A vaccine was included in the national planned immunization in 2007, and most areas in China have changed from high-prevalence areas to medium-or low-prevalence areas.

  2. Hepatitis B

  With the introduction of hepatitis B vaccine into the planned immunization in 1992, the incidence of hepatitis B in China dropped sharply. During the three national surveys in 2014, the HBsAg positive rate of people aged 1-29 in China decreased from 10.1% to 2.6%.

  Half of the world’s liver cancer patients are in China, and more than 80% of them are caused by hepatitis B. Effective prevention and control of hepatitis B can effectively reduce the occurrence of liver cancer, and it is also a successful case of preventing tumors through vaccines.

  Although hepatitis B has not been completely cured, it is controllable. With the development of new drugs, patients with chronic hepatitis B can effectively control the progress of the disease, block the progress to cirrhosis and liver cancer, and even reverse some decompensated cirrhosis to compensatory cirrhosis and maintain stability.

  In 2014, the fourth national hepatitis B serological survey showed that the positive rates of HBsAg among people aged 1-4, 5-14 and 15-29 were 0.3%, 0.9% and 4.4% respectively. It can be seen from this data that the incidence of hepatitis B virus infection has been effectively controlled by hepatitis B vaccination in the younger age group. It is believed that with the passage of time, the occurrence of hepatitis B virus infection will eventually be eliminated.

  3. Hepatitis C

  Hepatitis C is a chronic disease caused by hepatitis C virus (HCV) infection. The disease progresses continuously and can develop into cirrhosis and liver cancer. In recent years, a large number of direct antiviral drugs (DAA) have been put on the market, and hepatitis C has become a curable chronic viral disease, setting a precedent for curing chronic viral diseases through drug treatment intervention. Of course, there are still some problems in its treatment, such as drug accessibility and drug interaction.

  HCV infection in China is a low epidemic area in the world. The national seroepidemiological survey in 2006 showed that the positive prevalence rate of HCV antibody was 0.43% among people aged 1-59. HCV is mainly transmitted through blood and damaged skin and mucosa. In China, HCV antibody screening for blood donors began in 1993, and HCV RNA screening for blood donors with negative HCV antibody began in 2015. Since then, transmission through blood transfusion and blood products has rarely occurred.

  Hepatitis C progresses slowly and invisibly, and is often called "silent killer". Patients often lose the best opportunity for treatment as soon as they find cirrhosis or liver cancer. Therefore, people with high risk of HCV infection should take the initiative to go to the hospital for screening.

  4. Hepatitis D

  Hepatitis D is an acute and chronic hepatitis disease caused by hepatitis D virus (HDV), which is contagious. HDV is a small RNA virus with gene defect, and its replication and transmission must depend on the existence of hepatitis B virus (HBV). Compared with HBV infection alone, HDV with HBV infection is more serious and can rapidly progress to cirrhosis or even liver cancer. Because its infection depends on HBV, improving the vaccination rate of HBV is an effective measure to prevent HDV infection.

  5. Hepatitis E

  Diseases that are "from mouth to mouth" have a relatively high incidence among the elderly. Outbreaks or pandemics often occurred in China before 2000. After 2000, with the improvement of China’s economic level and health facilities, its epidemic was controlled, but attention should be paid to preventing local outbreaks.

  (6) Prevention and control of epidemic hemorrhagic fever

  Epidemic hemorrhagic fever, also known as hemorrhagic fever with renal syndrome, is caused by a group of viruses belonging to Hantavirus. Rats are the main source of infection and spread in many ways, with fever, hypotensive shock, congestive bleeding and renal damage as the main manifestations. An epidemic broke out in China in 1980s, with an annual incidence of more than 100,000 cases and a mortality rate of over 10%.

  The Party and the state attach great importance to the prevention and treatment of epidemic hemorrhagic fever. Under the leadership of the former Ministry of Health, the Branch of Infectious Diseases and Parasitology of the Chinese Medical Association established the epidemic hemorrhagic fever study group. As Professor Dan Ping served as the team leader, it organized domestic clinical experts to carry out clinical diagnosis and treatment research on hemorrhagic fever. The prevention and treatment plan of epidemic hemorrhagic fever in China was formulated, and a series of effective diagnosis and treatment plans such as preventive treatment were put forward, which greatly reduced the incidence and mortality of hemorrhagic fever.

  Second, pay tribute to the predecessors:

  They have made outstanding contributions to the development of infectious diseases in China.

  After the founding of New China, many predecessors made great contributions to the prevention and treatment of infectious and parasitic diseases in China.

  (1) Zhong Huilan

  The first honorary chairman of the branch of infectious diseases and parasitology of Chinese Medical Association. Physicians, tropical pathologists and medical parasitologists devoted their lives to the study of internal diseases, especially tropical diseases, and made pioneering research on the etiology, epidemiology, clinical diagnosis, treatment and prevention of relapsing fever, typhus, kala-azar, paragonimiasis and leptospirosis. Established the Institute of Tropical Diseases of Beijing Friendship Hospital. The pathogens of epidemic typhus and endemic typhus were separated, and it was confirmed that crabs could also spread typhus. It is suggested that bone marrow puncture instead of spleen puncture and complement fixation test should be used for early diagnosis of kala-azar. We cooperated with Feng Lanzhou to study the vector of kala-azar, and confirmed that the sandfly is the main vector of kala-azar near Beijing. To confirm the role of dogs as storage hosts in transmission. In the study, I was infected by accident, and combined with my experience and observation of other cases, I put forward the clinical types of early manifestations of kala-azar. A series of diagnosis and treatment norms have been formulated to guide clinical diagnosis and treatment.

  (2) Wu Chaoren

  He used to be the vice president and director of internal medicine of the First Hospital of Peking University (formerly the First Affiliated Hospital of Beijing Medical College), and he had high attainments in bacteriology research. In 1955, he founded the Infectious Diseases Department of the First Hospital of Peking University, and established the virus research room, parasitic disease research room and antibiotic research room (predecessor of Peking University Institute of Clinical Pharmacology). After 1963, he mainly conducted clinical antibiotic research, which made contributions to the development of antibiotic clinical research in China. Participate in the editor-in-chief of Infectious Diseases and other works. Together with Professor Zhong Huilan and Professor Cao Zhongliang, they set up the Infectious Diseases and Parasitology Group of the Chinese Medical Association (the predecessor of the Infectious Diseases Branch of the Chinese Medical Association), actively carried out academic exchange activities, and held the first national academic conference on viral hepatitis in Changchun in 1962 and the first national academic conference on infectious diseases in Huangshan in 1963, which made great contributions to the development of infectious diseases.

  (3) Wang Jiwu

  The first chairman of the Branch of Infectious Diseases and Parasitology of Chinese Medical Association, a famous expert in internal medicine and infectious diseases and medical educator, the founder of the Department of Infectious Diseases and Parasitology of Zhejiang University, edited the first infectious diseases masterpiece — — Epidemiology has played an important role in the training of talents and teachers in the field of epidemiology, as well as in the diagnosis and treatment of schistosomiasis, viral hepatitis and leptospirosis.

  (4) Cao Zhongliang

  As a famous medical educator and infectious disease scientist in China, from controlling cholera epidemic before the founding of New China to eliminating schistosomiasis after the founding of New China, as a leading figure in southwest China, he personally organized diagnosis and treatment on the spot. When there was a leptospirosis epidemic in Sichuan in 1958, he went to the scene to rescue critically ill patients, and then insisted on field research for 30 years. In the field of leptospirosis pulmonary hemorrhage, Huaxi Medical College has established a leading position at home and abroad. Viral hepatitis, especially severe jaundice ascites hepatitis, was also studied in depth.

  (5) Mao Shoubai

  Medical parasite expert, one of the pioneers of schistosomiasis research in China. In the fields of schistosomiasis epidemiology, immunodiagnosis, experimental treatment, snail control methods and schistosomiasis biology, it has achieved practical scientific research achievements recognized by peers at home and abroad. In 1984, he won the "Leon Birna" prize in the 37th World Health Assembly, which was the first time that a Chinese scholar won this honor.

  (6) Dai Ziying

  The first vice chairman of the branch of infectious diseases and parasitology of Chinese Medical Association. Firstly, the scheme of treating typhoid fever and paratyphoid fever with low dose of chloramphenicol was put forward. Leading the diagnosis, treatment and research of viral hepatitis and hemorrhagic fever, and the pathogenesis and treatment of sepsis and septic shock. Combining clinical medicine, clinical microbiology and clinical pharmacology, he is the founder of clinical antibiotics in China. Editor-in-chief of Clinical Antibiotics and other works. 1971— In 1972, he led the investigation of clinical application of sulfa drugs, penicillin and streptomycin in China. 1978— In 1981, tetracycline antibiotics were re-evaluated, and suggestions to restrict the use of these drugs were put forward and adopted by the health administrative department. He has made outstanding achievements in advocating the rational use of antibiotics in China.

  (7) Tian Gengshan

  Chairman of the Second and Third Committees of Infectious Diseases and Parasitology Branch of Chinese Medical Association. During his tenure as deputy director of the former viral hepatitis expert advisory Committee of the Ministry of Health, he organized domestic experts to make suggestions to the state to carry out hepatitis B vaccination for newborns, which was formally included in the planned immunization management by the Ministry of Health, and played an important role in reducing the incidence of hepatitis B. Organized multi-center clinical trials for many times, creating a precedent for multi-center clinical research in infectious diseases in China. He presided over the formulation of China’s "Virus Hepatitis Prevention and Control Program" twice.

  (8) Wang Juntao

  Chairman of the Fourth Session of Infectious Diseases and Parasitology Branch of Chinese Medical Association. He used to be the vice president of Beijing Second Infectious Disease Hospital (Beijing You ‘an Hospital). Focusing on viral hepatitis, he served as the head of the national key project "Pathogenesis of Chronic Active Hepatitis B and Evaluation of Therapeutic Drugs" during the Sixth Five-Year Plan.

  (9) Wang Aixia

  Chairman of the Fifth Session of Infectious Diseases and Parasitology Branch of Chinese Medical Association. The first case of AIDS patients and the first case of sexually transmitted human immunodeficiency virus (HIV) infection in China were found and reported, and anti-HIV drugs were first used to treat HIV infection in China. In 1995, the national standards for AIDS diagnosis and treatment were formulated. He was the first in China to study the trend of nosocomial infection bacteria, took the lead in completing the prospective epidemiological investigation of hepatitis C after blood transfusion, and took the lead in proposing to be alert to cross-infection of hepatitis C caused by blood transfusion. First of all, it advocates that the branch of infectious diseases and parasitology should return to the essence of infectious diseases, and the infectious diseases department should be renamed as infectious diseases department.

  (10) Si Chongwen

  Chairman of the Sixth Committee of Infectious Diseases and Parasitology Branch of Chinese Medical Association, formally applied to rename the Branch of Infectious Diseases and Parasitology of Chinese Medical Association as Infectious Diseases Branch of Chinese Medical Association during his term of office. During his term of office, he organized experts to revise the Prevention and Treatment Plan of Viral Hepatitis in 2000, which effectively guided clinical practice. The Committee for Young and Middle-aged People was established, and the first national conference for young and middle-aged people with infectious diseases was held. The AIDS group and the artificial liver group were established. Editor-in-chief of the first monograph of Infectious Diseases.

  (xi) Weng Xinhua

  The 7th Chairman of Infectious Diseases Branch of Chinese Medical Association, during his tenure, Infectious Diseases and Parasitology Branch of Chinese Medical Association was officially renamed as Infectious Diseases Branch of Chinese Medical Association. In-depth clinical practice and research have been carried out on the etiological diagnosis of long-term unexplained fever, bacterial infectious diseases and viral hepatitis, and the ability of diagnosis and treatment of bacterial and fungal infections in China has been actively promoted. During his tenure as chairman, he presided over the compilation of China’s Guidelines for the Prevention and Treatment of Chronic Hepatitis B and Hepatitis C..

  (XII) Li Lanjuan

  The 8th and 9th Chairman of Infectious Diseases Branch of Chinese Medical Association, Academician of China Academy of Engineering. Director of State Key Laboratory of Infectious Diseases Diagnosis and Treatment, Director of Collaborative Innovation Center for Infectious Diseases Diagnosis and Treatment. Editor-in-chief has published 35 monographs such as Artificial Liver, Infectious Microecology and Infectious Diseases, which are the first textbooks in China. He won one special prize of the National Science and Technology Progress Award, one national science and technology progress award (innovation team), two first prizes and two second prizes, and was awarded the titles of "National Excellent Scientific and Technological Worker" and "National Outstanding Professional and Technical Talent", the Science and Technology Progress Award of Heliang Heli Fund, Guanghua Engineering Science and Technology Award and Tan Jiazhen Science Award for Clinical Medicine.

  (13) Hou Jinlin

  The 10th Chairman of Infectious Diseases Branch of Chinese Medical Association. During his term of office, he actively promoted the prevention and treatment of viral hepatitis and promoted international exchanges and cooperation. As the chairman of the Asia-Pacific Liver Disease Research Association, he hosted the largest annual meeting of Asia-Pacific liver diseases, which improved the academic discourse power of viral hepatitis and liver diseases research in China in the international arena. Presided over the "small shell" project to strengthen the standardized management of mother-to-child blocking of hepatitis B.

  Third, towards the future:

  The road of "big infection" in infectious diseases

  (1) Learn to change its name,

  "Infectious Diseases" has officially entered history.

  In 2002, in order to conform to the development trend of the discipline, under the initiative of many predecessors in the field of infectious diseases, the Chinese Branch of Infectious Diseases and Parasitology was officially renamed as the Infectious Diseases Branch of the Chinese Medical Association, and the website of the Infectious Diseases Branch of the Chinese Medical Association was established, which was the earliest website among the branches of the Chinese Medical Association.

  At that time, the predecessors of infectious diseases had realized that the infectious diseases discipline in China should change from classical infectious disease prevention and control to viral hepatitis and liver disease diagnosis and treatment, and return to the major infectious diseases discipline. The predecessors saw the development direction of infectious diseases in China in time, and put forward that we should strengthen the capacity building of diagnosis and treatment of bacterial and fungal infections. The renaming of the Society points out the direction for the development of infectious diseases.

  It can be said that the development of infectious diseases in China has entered the third stage, returning to the essence of infectious diseases, that is, the construction of "big infection" discipline with the improvement of the ability of diagnosis and treatment of bacterial and fungal infections.

  (B) the construction of the "big infection" discipline,

  Improving the ability of diagnosis and treatment of bacterial and fungal infections is "king"

  In fact, as early as 1970s and 1980s, Professor Dai Ziying and Professor Xu Zhaoyue of Shanghai Huashan Hospital realized the importance of improving the ability of diagnosis and treatment of bacterial and fungal infections. They have published many books on the rational use of antibacterial drugs and done a lot of forward-looking work, which laid a solid foundation for the establishment of the Institute of Antibiotics in Huashan Hospital affiliated to Fudan University. Up to now, the Institute of Antibiotics of Huashan Hospital affiliated to Fudan University and the Institute of Clinical Pharmacology of Peking University have played an important role in the research and development of antibacterial drugs, clinical trials and related personnel training in China.

  At present, the global situation of bacterial drug resistance is grim, and all countries in the world attach great importance to the problem of bacterial drug resistance. An expert group in Britain predicts that if the current situation of bacterial drug resistance is not solved, by 2050, the death of patients caused by drug-resistant bacteria infection will return to the first place in the world.

  China attaches great importance to the prevention and control of bacterial and fungal drug resistance. In 2012, the former Ministry of Health issued the first "Management Measures for Clinical Use of Antibacterials", which clearly stipulated that infectious diseases departments should participate in the management of rational use of antibacterial drugs. However, the status quo that cannot be ignored is that most infectious diseases doctors in China are still mainly engaged in the diagnosis and treatment of viral hepatitis and liver disease, and the ability of diagnosis and treatment of bacterial and fungal infections needs to be improved urgently.

  In 2016, the National Health and Wellness Commission issued the "Notice on Improving the Diagnosis and Treatment Capability of Bacterial Fungi in General Hospitals above Grade II", emphasizing that general hospitals above Grade II should set up infection departments and establish a diagnosis and treatment system of bacterial fungal infections with infectious diseases as the main body, which provides a clear orientation for the future development of infectious diseases.

  At the beginning of the 11th Committee of Infectious Diseases Branch of Chinese Medical Association, Chairman Wang Guiqiang clearly put forward the construction plan of infectious diseases discipline, and strengthened the promotion of the ability of diagnosis and treatment of bacterial and fungal infections. On the one hand, it is closely related to the national policy orientation; on the other hand, it shows that the infectious diseases academic circles in China have realized that the infectious diseases academic circles should actively participate in the application and management of antibacterial drugs, especially strengthen their own improvement in the diagnosis and treatment of bacterial and fungal infections, so as to cope with the increasingly severe drug resistance situation of bacterial and fungal infections.

  (3) Do a good job in the discipline construction of "big infection",

  Infection department, clinical microbiology and hospital infection control are indispensable.

  Bacterial and fungal infections are distributed in various clinical departments. In addition to clinical diagnosis and treatment of infectious diseases, the infectious diseases department also provides strong support for the prevention and control of infectious diseases in the whole hospital. If the ability of infection doctors is weak, the ability of diagnosis and treatment of bacterial and fungal infections in the whole hospital will be weak. At present, the state emphasizes the rational use of antibacterial drugs and the control of medical expenses, which will greatly increase the medical expenses, prolong the hospitalization time and increase the mortality rate after the occurrence of concurrent infection, especially drug-resistant bacteria infection. Effective control of infection and effective diagnosis and treatment of infectious diseases can significantly improve the operating efficiency of hospitals. Therefore, from the perspective of hospital management, it is very important to do a good job in the construction of infectious diseases.

  To do a good job in the construction of "big infection" discipline, on the one hand, the infectious disease discipline should strengthen its own ability improvement and talent echelon construction, on the other hand, it is also very important to do a good job in pathogen diagnosis and nosocomial infection management. Therefore, infectious diseases, clinical microbiology and nosocomial infection management should be organically combined to integrate subject resources, strengthen subject cooperation, and form a joint force to jointly do a good job in the diagnosis and treatment of infectious diseases.

  In addition, hospital management departments and national health administrative departments should also attach importance to the construction of infectious diseases disciplines and provide corresponding support for the construction of infectious diseases disciplines.

  Fourth, the outlook

  At present, although the outbreak of infectious diseases is abnormal, we should always be vigilant and effectively control new and sudden infectious diseases in time. Therefore, on the one hand, the Department of Infectious Diseases undertakes the classical infectious diseases such as public health, prevention and control of classical infectious diseases, and on the other hand, although the incidence of viral hepatitis has been effectively controlled, the existing infected population base is still large, and infectious doctors still undertake a large number of viral hepatitis and liver disease prevention and control work. In addition, infection doctors need to improve the ability of diagnosis and treatment of bacterial fungi and fever of unknown origin, and play a role in the rational use of antibacterial drugs. At the same time, it is hoped that infection doctors will actively participate in the prevention and control of nosocomial infection and the interpretation of clinical microbial results, so as to improve the diagnosis and treatment ability of pathogenic microbial infections in China.

  Finally, Professor Wang Guiqiang pointed out that the future development direction of infectious diseases discipline has been made clear, and our generation is a connecting link. We hope that through our efforts, the infectious diseases discipline will be built more comprehensively and with stronger capabilities, so as to meet the requirements of the national health strategy and escort the healthy China strategy.

  Five, subject files:

  Memorabilia of China Infectious Diseases Department

  In 1950, the Ministry of Health promulgated the "Interim Measures for Vaccinium Vaccination" to promote free vaccination throughout the country. Beijing promulgated the Interim Measures for the Prevention and Treatment of Infectious Diseases.

  In 1955, the first Measures for the Management of Infectious Diseases was promulgated and implemented by the Ministry of Health. Infectious diseases departments have been set up in university affiliated hospitals all over the country.

  In 1961, China announced the complete eradication of smallpox virus, 19 years earlier than the World Health Organization announced that smallpox had been eradicated all over the world.

  In 1978, the Ministry of Health issued the Regulations of the People’s Republic of China on the Management of Acute Infectious Diseases, which stipulated that there were 25 kinds of infectious diseases in two categories.

  In 1979, after the founding of People’s Republic of China (PRC), the first masterpiece of epidemiology was published.

  In 1980, the Branch of Infectious Diseases and Parasitology of Chinese Medical Association was formally established. The Ministry of Health issued the Measures for the Implementation of Vaccination.

  In 1982, the Ministry of Health issued the National Regulations on Planned Immunization, which clarified the vaccines used and unified the immunization procedures for children.

  In 1985, the first case of AIDS in China was found among tourists coming to China.

  In 1989, China’s first Law on the Prevention and Control of Infectious Diseases in People’s Republic of China (PRC) was passed and came into force on September 1st.

  Since January 1, 1992, hepatitis B vaccine immunization has been popularized all over the country, and it has been gradually incorporated into children’s planned immunization.

  In 2000, the WHO Western Pacific Regional Polio Eradication Confirmation Committee declared China polio-free.

  In 2002, the Branch of Infectious Diseases and Parasitology of Chinese Medical Association was officially renamed as the Branch of Infectious Diseases of Chinese Medical Association, and a website was established, which was the earliest website among all branches, and the infectious diseases departments of general hospitals were renamed as infectious diseases departments one after another. The Chinese Academy of Preventive Medicine was renamed China Center for Disease Control and Prevention.

  In 2003, a large-scale SARS epidemic broke out in China.

  In 2004, China launched the largest infectious disease surveillance network in the world. The revised Law on the Prevention and Control of Infectious Diseases came into force on December 1st.

  In 2005, the Guidelines for the Prevention and Treatment of Chronic Hepatitis B and the Guidelines for the Prevention and Treatment of Hepatitis C were released, which were updated in 2010 and 2015 respectively, and the fourth edition is currently being revised.

  In 2008, the Ministry of Health issued the Guidelines for the Prevention and Control of Hand, Foot and Mouth Disease (2008 Edition), which included hand, foot and mouth disease in the management of Class C infectious diseases.

  In 2009, the Ministry of Health issued a public announcement, explicitly including influenza A (H1N1) as a Class B infectious disease under the management of the Law on the Prevention and Control of Infectious Diseases, and taking measures to prevent and control Class A infectious diseases.

  In 2012, the Administrative Measures for Clinical Application of Antibacterials was officially promulgated and implemented on August 1st. The vast majority of counties (cities) in China have basically eliminated leprosy (taking counties and cities as units, the prevalence rate is ≤ 0.01‰ , the average annual incidence or detection rate in recent 5 years ≤ 0.5/100,000) standard.

  In 2013, the National Health and Family Planning Commission issued the "Notice on Adjusting the Management of Some Legal Infectious Diseases" to include human infection with H7N9 avian influenza as a legal Class B infectious disease; Adjust influenza A (H1N1) from Class B to Class C and bring it into the existing influenza for management; Lift the prevention and control measures for Class A infectious diseases stipulated in the Law on the Prevention and Control of Infectious Diseases for people infected with highly pathogenic avian influenza.

  In 2016, the only EV71 vaccine that can be used to prevent hand, foot and mouth disease was born in China.

  In 2018, led by Academician Li Lanjuan, director of the State Key Laboratory of Infectious Diseases Diagnosis and Treatment of Zhejiang University and the Collaborative Innovation Center for Infectious Diseases Diagnosis and Treatment, and jointly completed by 11 units including China Center for Disease Control and Prevention, the project of "Major Innovation and Technological Breakthrough in the Prevention and Control System of Emerging Infectious Diseases Represented by the Prevention and Control of Human Infections with H7N9 Avian Influenza" won the special prize of the 2017 National Science and Technology Progress Award.